Beilstein J. Org. Chem.2014,10, 741–745, doi:10.3762/bjoc.10.68
(benzyloxycarbonylamino)(aryl)methylphosphonic acids is described by means of the Oleksyszynreaction. The library was enlarged by the application of a Suzuki–Miayra approach and by preparation of mixed esters.
Keywords: aminophosphonates; Oleksyszynreaction; organophosphorus; Z-aminophosphonate esters; Introduction
aldehydes and benzyl carbamates (the so called Oleksyszynreaction) for the synthesis of fluorescent (benzyloxycarbonylamino)(aryl)methylphosphonates.
Results and Discussion
Synthesis of diaryl (benzyloxycarbonylamino)(phenyl)methylphosphonates
Diaryl esters of Z-protected aminobenzylphosphonic acid were